Composite
Part:BBa_K3440005:Design
Designed by: Aditi Kallai, Julie Cordier Group: iGEM20_Stockholm (2020-10-23)
Lux I with myc tag under Promoter prmA activated in the presence of PFOS
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21INCOMPATIBLE WITH RFC[21]Illegal BglII site found at 837
Illegal BglII site found at 875 - 23COMPATIBLE WITH RFC[23]
- 25INCOMPATIBLE WITH RFC[25]Illegal NgoMIV site found at 137
Illegal NgoMIV site found at 148 - 1000COMPATIBLE WITH RFC[1000]
Design Notes
This part was designed to show that LuxI can be expressed under prma promoter, and to compare expression with/without PFOS. This was used as our final construct in our E. coli module to detect PFOS. A moderate RBS (BBa_B0034) was used. A myc-tag was added for characterization.
Source
LuxI is from Aliivibrio fischeri (Vibrio fischeri) and pprmA is from Rhodococcus jostii (strain RHA1)